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CYCLIN-DEPENDENT KINASE 8
Descriptors Found:
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DeCS
Descriptor
English
:
Cyclin-Dependent Kinase 8
Descriptor
Spanish
:
Quinasa 8 Dependiente de Ciclina
Descriptor
Portuguese
:
Quinase 8 Dependente de Ciclina
Tree Number:
D05.500.374.500
D08.811.913.696.620.682.700.200.547
D12.644.360.024.304.500
D12.644.360.250.547
D12.776.157.057.062.500
D12.776.476.024.388.500
D12.776.660.551.500
Definition
English
:
A
CYCLIN C
dependent kinase that is an important component of the
mediator complex
. The enzyme is activated by its interaction with
CYCLIN C
and plays a
role
in transcriptional regulation by phosphorylating
RNA POLYMERASE II.
History Note
English
:
2010
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53575
Unique Identifier:
D056850
Occurrence in VHL
:
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DeCS
CID-10
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